Research involving a potent antioxidant, described on September 19, 2017 in Scientific Reports, suggests that the compound could help protect cells in several conditions, including Parkinson’s disease, multiple sclerosis and cell transplants. In their report, a team from the University of Edinburgh observe that the flavonoids quercetin and myricetin are among the most potent dietary antioxidants. Structural modification of myricetin has resulted in the development a new compound known as Proxison. In the current research, Proxison demonstrated 10 times the ability to protect against oxidative stress induced by the compound tert-Butyl hydroperoxide (tBHP) in neuroblastoma cells compared to quercetin, while several other antioxidants […]
An article appearing August 21, 2017 in Nature Medicine reveals a potential role for senolytic compounds, including quercetin and the drug dasatinib, in the targeting of senescent cells to help maintain bone. “While we know from previous work that the accumulation of senescent cells causes tissue dysfunction, the role of cell senescence in osteoporosis up to this point has been unclear,” noted researcher Sundeep Khosla, MD, of the Mayo Clinic’s Robert and Arlene Kogod Center on Aging. “The novelty of this work for the bone field lies in the fact that, rather than targeting a bone-specific pathway, as is the case for all current […]
Inflammation is traditionally thought of as a symptom of sleep apnea, but it might actually precede the disorder,
The August 10, 2017 issue of Cell reported an ability for calorie restriction to prevent the impact of aging on circadian rhythms. “The process of aging and circadian rhythms are intimately intertwined, but how peripheral clocks involved in metabolic homeostasis contribute to aging remains unknown,” the authors write in their introductory remarks. For the current investigation, researchers at the University of California, Irvine fed calorie restricted or unrestricted diets to young and old mice. At 6 and 18 months, liver tissue samples were analyzed. Although calorie restriction did not affect the 24-hour cycle of the older group’s circadian-controlled metabolic system, older cells showed signs […]
An article appearing on August 21, 2017 in Nature describes research conducted at the University
The role of sun exposure in the formation of vitamin D in the body is well known. Now it appears that the vitamin may also play a role in protecting the skin from burning after being exposed to potentially damaging amounts of the sun’s ultraviolet (UV) rays. In a randomized trial reported on May 30, 2017 in the Journal of Investigative Dermatology, 20men and womenwere given 50,000 international units (IU), 100,000 IU or 200,000 IU vitamin D3, or a placebo one hour following ultraviolet UV lamp sunburn to the inner arm. The patients were examined 24 hours, 48 hours, 72 hours and […]
A recent study at University College London found low iron levels may increase a person’s risk of developing heart disease. Previous research has shown that iron status, the amount of iron in the body, is linked to cardiovascular disease, or CVD, risk. Researchers have struggled in the past to show a direct link and have often had conflicting results. “Previous studies have suggested a link between iron levels and heart disease, but it has been difficult to pick this apart from other confounding factors,” Dr. Dipender Gill, a Wellcome Trust Clinical Fellow at Imperial College London, said in a press release. The current study, […]
Doctors say there’s no connection between breast cancer and deodorants/antiperspirants. But has this
A few common foods may help rein in the chronic inflammation that contributes to so many diseases. A new study by the University of Liverpool’s Institute of Ageing and Chronic Disease found that the polyphenols in onions, apples turmeric, grapes, onions, green tea and açai berries may be key to fighting the swelling. To hone in on which foods might be most helpful in halting inflammation, scientists tested 31 polyphenols and six polyphenol combos to see how they affected T-cells in the blood. T-cells are a type of white blood cell that circulates throughout our bodies, scanning for cellular abnormalities. Through cell-signaling molecules called cytokines, they call […]
You’ve likely heard of Juniper as a trendy additive in foods, often used as a culinary condiment or a flavor component in gin and bitter cocktail preparations. You will also find it as an extract and oil used as a flavoring agent in a variety of foods and beverages. Aside from these culinary uses, juniper is also used medicinally, especially as a diuretic and anti-diabetic agent and there are some really important considerations to know about when considering juniper used for these conditions. Juniper, officially Juniperus communis, is used therapeutically in oral form in capsules, tinctures or oils for a variety […]
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