The 2015 American Society of Cancer Oncology (ASCO) Gastrointestinal Cancers Symposium held in San Francisco was the site of a presentation on January 12, 2015 concerning the finding of longer average survival among colorectal cancer patients with higher vitamin D levels in comparison with those whose levels were low. Researchers at Dana-Farber Cancer Institute analyzed data from 1,043 patients with colorectal cancer enrolled in a clinical trial that evaluted the effects chemotherapy plus the biologic therapies bevacizumab and/or cetuximab. Plasma 25-hydroxyvitamin D levels were measured at the beginning of the study and dietary questionnaire responses were analyzed for vitamin D intake from […]
I (John Cannell, MD) recently learned that I have the Broad Autism Phenotype, or what some people call mild autism. Learning about this was like “coming out of the closet.” It explains so much of myself to me, especially my tendency to get obsessed with things.
An article published online on December 17, 2014 in the Journal of Nutrition reports the outcome of a double-blinded trial of overweight and obese men and women which found a protective role for whey protein supplementation against some of the loss of muscle that occurs with dieting. Researchers at Canada’s McMaster University randomized 19 men and 21 women to receive a fourteen day low calorie diet supplemented with 27 grams whey protein or 26 grams soy protein (resulting in the intake of an average of 1.3 grams protein per kilogram per day), or the addition of carbohydrate providing a number of calories equal to […]
Any meat (including fish) cooked at high temperatures creates dangerous carcinogens. Scientists looked at men whose diets included high intake of red meat cooked at high temperatures, pan-fried, or well-done. Their findings published in 2012 showed specific gene expression changes that predisposed these men to advanced prostate cancer. These kinds of studies show that one can exert a degree of control over their cell regulatory genes by avoiding overcooked meats. Aggressive malignancies are those that rapidly propagate, infiltrate and metastasize. A 2011 study evaluated almost 1,000 men and found that higher consumption of any ground beef or processed meats was associated with an increased risk of aggressive prostate cancer. Men who ate […]
We all dream of our babies inheriting what we consider our best qualities: patience, spontaneity, cleverness, or ocean blue eyes. What we don’t want is to pass celiac on to our little ones. Many parents have this concern, and there is a lot of new research and information available that better clarifies what we need to know about babies and celiac. What are the symptoms? When should my baby be tested? Should I give my baby gluten, or avoid it entirely? Is there anything I can do to help prevent celiac from developing? There may just be. Celiac, which […]
An article that appeared in the journal Allergy on October 3, 2014 revealed an association between vitamin D deficiency and the risk of asthma exacerbations. The study included 307,900 men and women whose serum 25-hydroxyvitamin D levels were measured between 2008 and 2012. Among them, 21,237 had been diagnosed with asthma. Asthma exacerbations were considered to have occurred among subjects who were prescribed oral corticosteroids, who received more than five prescriptions for short acting beta agonists, or who had more than four asthma-related physician visits. Although vitamin D levels were similar between asthmatics and nonasthmatics, vitamin D deficiency in the asthmatic population was associated […]
Alzheimer’s disease affects over 13 million people worldwide. Many of my patients fear this most common form of dementia, and with good reason. The disease is not completely understood, and it is not possible to predict who will fall victim. With treatment costs for Alzheimer’s topping 100 billion dollars in the United States alone, the medical community is eager to unlock the mysteries of this disease. In my review of recent studies on Alzheimer’s, I found plenty of promising news. A handful of studies show that your eating habits in middle age can have an effect on your Alzheimer’s risk. […]
I think this is the most excited I’ve ever been for the development of a product to help us folks who eat a gluten-free diet. Do I have you on the edge of your seat now? A company called 6SensorLabs is currently building a device which will allow you to check your food for gluten and see the results in real-time on your mobile phone. This is huge news, because I (and many of you) get sick and worry about getting sick far too often. Even the most well-intentioned wait staff and chefs are sometimes unaware of gluten hiding in […]
The results of a meta-analysis published in a recent issue of the American Journal of Clinical Nutrition add evidence to preliminary findings concerning a protective effect for soy against the development of lung cancer.* Yong-Bing Xiang of Shanghai Jiaotong University School of Medicine and colleagues selected eight case-control and three prospective cohort studies for their review, which included 8,436 cases of lung cancer. The analysis uncovered a 23% reduction in lung cancer risk in association with high versus low soy consumption. When the analysis was limited to five studies of high quality, a 30% reduction was revealed. In analyses of specific groups, […]
Malignant mesothelioma, a cancer of the lining of the lungs that is largely attributable to asbestos exposure, could face a worthy opponent in the form of curcumin, a compound that occurs in the spice turmeric, according to research reported in October 2014 issue of Clinical Cancer Research. Ashfin Dowlati and colleagues at University Hospitals Case Medical Center in Cleveland measured mesothelioma tumor expression of PIAS3 (protein inhibitor of activated STAT3), which is correlated with overall survival. They additionally evaluated the effects of PIAS3 activity on the intracellular protein and transcription factor STAT3 (signal transducer and activator of transcription 3), which can trigger cancer […]
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