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                      Counting Calories Could Prevent Diseases

                      Published by Life Extension

                      Healthy lunch in boxes

                      Research presented on February 11, 2019 at FAPESP (São Paulo Research Foundation) Week London supports the potential for calorie restriction to protect against several diseases. The studies were conducted under the auspices of the Center for Research on Redox Processes in Biomedicine, which is funded by FAPESP. “We are looking at how changes to the diet affect metabolism and how that ends up changing the odds of having diseases associated with aging,” commented researcher Alicia Kowaltowski, of the University of São Paulo.

                      In one experiment, a group of mice was allowed to consume as much food as they desired, and the number of calories consumed daily was calculated. Another group was given a diet that contained 40% fewer calories than the number consumed by the unrestricted mice. After two weeks, the animals received injections of a compound that causes seizures and the death of neurons. Mice that received low calorie diets were protected against seizures, which suggests an ability of calorie restriction to prevent the death of neurons that characterizes neurodegenerative diseases.

                      In other research, blood serum from mice given varying amounts of calories was administered to cultured beta cells (which produce insulin). Cells treated with serum from animals who consumed fewer calories exhibited normal insulin secretion, while beta cells from animals who consumed a high number of calories and became obese did not release insulin normally. “Obese individuals are much more likely to have age-related diseases,” Dr Kowaltowski noted. “This includes neurodegenerative diseases like Alzheimer’s, proliferative diseases like cancer, and metabolic diseases themselves, such as type 2 diabetes, hyperlipidemia, heart attack and cerebrovascular accident.”

                      “That’s why if we try to understand the mechanisms through which obesity increases those diseases, we will have more tools to fight and prevent them,” she concluded.

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                      Life Extension
                      Life Extension
                      LIFE EXTENSION The Life Extension Health News team delivers accurate information about vitamins, nutrition and aging. Our stories rely on multiple, authoritative sources and experts. We keep our content accurate and trustworthy, by submitting it to a medical reviewer. Life Extensionists are people who believe in taking advantage of documented scientific therapies to help maintain optimal health and slow aging. The medical literature contains thousands of references on the use of antioxidant vitamins, weight loss supplements, and hormones that have been shown to improve the quality and quantity of life. Life Extensionists attempt to take advantage of this scientific information to enhance their changes of living longer in good health. This article is posted by permission of Life Extension. https://www.lifeextension.com/

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                      This website is for informational and entertainment purposes only and is not a substitute for medical advice, diagnosis or treatment. FoodTrients – A Recipe for Aging Beautifully Grace O, author and creator of FoodTrients® -- a philosophy, a cookbook and a resource -- has a new cookbook dedicated to age-defying and delicious recipes, The Age Beautifully Cookbook: Easy and Exotic Longevity Secrets from Around the World, which provides one hundred-plus recipes that promote health and well-being. The recipes are built on foundations of modern scientific research and ancient knowledge of medicinal herbs and natural ingredients from around the world. Since the publication of her first anti-aging book, The Age GRACEfully Cookbook, Grace O has identified eight categories of FoodTrients benefits (Anti-inflammatory, Antioxidant, Immune Booster, Disease Prevention, Beauty, Strength, Mind, and Weight Loss) that are essential to fighting aging, which show how specific foods, herbs, and spices in the recipes help keep skin looking younger, prevent the diseases of aging, and increase energy and vitality. Grace O combines more exotic ingredients that add age-fighting benefits to familiar recipe favorites.

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