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                      Can Grape Seed Extract Prevent Colon Cancer?

                      Published by Life Extension

                      Grape seed oil in brown bottle, bunch of grapes, vine

                      Research conducted at Pennsylvania State University indicates that grape seed extract and resveratrol, which occurs in red grapes, can suppress colon cancer stem cells. The study was reported in BMC Complementary and Alternative Medicine.

                      “We are particularly interested in targeting stem cells because, according to cancer stem-cell theory, cancerous tumors are driven by cancer stem cells,” explained coauthor Jairam K.P. Vanamala, who is an associate professor of food sciences at Penn State. “Cancer stem cells are capable of self-renewal, cellular differentiation and maintain their stem cell-like characteristics even after invasion and metastasis.”

                      In human colon cancer stem cell cultures, a combination of resveratrol and grape seed extract suppressed proliferation and other factors in a manner similar to the nonsteroidal anti-inflammatory drug sulindac, which has reduced tumors in humans. In mice with induced colon cancer, resveratrol and grape seed extract suppressed tumor incidence by more than 50%–an effect that was also comparable to that associated with sulindac. The combined effect of resveratrol and grape seed extract was associated with greater cancer stem cell suppression than either compound alone. “This also connects well with a plant-based diet that is structured so that the person is getting a little bit of different types of plants, of different parts of the plant and different colors of the plant,” stated Dr Vanamala, who is also a faculty member at the Pennsylvania State University Hershey Cancer Institute. “This seems to be beneficial for not only promoting bacterial diversity, but also preventing chronic diseases and eliminating the colon cancer stem cells.”

                      “The combination of resveratrol and grape seed extract is very effective at killing colon cancer cells,” he concluded. “And what we’re learning is the combination of these compounds is not toxic to healthy cells.”

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                      Life Extension
                      Life Extension
                      LIFE EXTENSION The Life Extension Health News team delivers accurate information about vitamins, nutrition and aging. Our stories rely on multiple, authoritative sources and experts. We keep our content accurate and trustworthy, by submitting it to a medical reviewer. Life Extensionists are people who believe in taking advantage of documented scientific therapies to help maintain optimal health and slow aging. The medical literature contains thousands of references on the use of antioxidant vitamins, weight loss supplements, and hormones that have been shown to improve the quality and quantity of life. Life Extensionists attempt to take advantage of this scientific information to enhance their changes of living longer in good health. This article is posted by permission of Life Extension. https://www.lifeextension.com/

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                      This website is for informational and entertainment purposes only and is not a substitute for medical advice, diagnosis or treatment. FoodTrients – A Recipe for Aging Beautifully Grace O, author and creator of FoodTrients® -- a philosophy, a cookbook and a resource -- has a new cookbook dedicated to age-defying and delicious recipes, The Age Beautifully Cookbook: Easy and Exotic Longevity Secrets from Around the World, which provides one hundred-plus recipes that promote health and well-being. The recipes are built on foundations of modern scientific research and ancient knowledge of medicinal herbs and natural ingredients from around the world. Since the publication of her first anti-aging book, The Age GRACEfully Cookbook, Grace O has identified eight categories of FoodTrients benefits (Anti-inflammatory, Antioxidant, Immune Booster, Disease Prevention, Beauty, Strength, Mind, and Weight Loss) that are essential to fighting aging, which show how specific foods, herbs, and spices in the recipes help keep skin looking younger, prevent the diseases of aging, and increase energy and vitality. Grace O combines more exotic ingredients that add age-fighting benefits to familiar recipe favorites.

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