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                      Melatonin Preserves Bone Mass

                      Published by Life Extension

                      Age-related bone loss is a serious condition. It not only increases the risk for fractures, but also increases the risk for death from heart and lung disease and all-cause death, especially if bone loss occurs quickly.

                      This is why it’s so important to stay active as we age, as this can preserve bone mass and strength. We also need to obtain adequate amounts of calcium, magnesium, and vitamins D and K2 through diet and supplementation.

                      For many aging people, however, this still isn’t enough. Bone loss continues despite all their efforts. This means that a lot of people end up taking prescription drugs called bisphosphonates. Unfortunately, although these drugs are effective at increasing bone density (but not necessarily bone strength), they also come bundled with a host of side effects. So what else can we do?

                      Melatonin – An Unlikely Natural Remedy

                      This is where melatonin comes into play. Yes, that’s correct … melatonin! The “sleep hormone” also protects our bones. This was first discovered in animal studies that showed melatonin’s potential effects as a bone mass regulator.

                      But these earlier studies were not done on older animals — in terms of bone health, older animals, including humans, is really the population we’re most interested in studying. Well, researchers have finally put melatonin to test with the appropriate population … in rats at least.

                      Old Rats, Old Bones and Melatonin

                      The aim of the study was to assess the effects of melatonin supplementation on bone mass and volume. Twenty 22-month-old male Wistar rats (that’s old for Wistar rats) were divided into two randomly assigned groups.

                      The first group was treated for 10 weeks with melatonin, whereas the second group was left untreated. Rat femurs were collected and analyzed.

                      Rats treated with melatonin had higher bone volume and thickness in comparison to the control group. Histological analyses (bone tissues analyzed using microscopes) confirmed the increase of bone volume in melatonin-treated rats.

                      Melatonin-treated rats also demonstrated higher bone stiffness and the ability to withstand greater tension, an indication of increased bone strength.

                      Melatonin Protects Against Age-related Bone Loss

                      These compelling results are the first evidence indicating that melatonin supplements are able to exert beneficial effects against age-related bone loss in old rats, improving the structure and biomechanical properties of aged bones.

                      Who knows? Perhaps humans can reap the bone benefits too. Only time will tell!

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                      Life Extension
                      Life Extension
                      LIFE EXTENSION The Life Extension Health News team delivers accurate information about vitamins, nutrition and aging. Our stories rely on multiple, authoritative sources and experts. We keep our content accurate and trustworthy, by submitting it to a medical reviewer. Life Extensionists are people who believe in taking advantage of documented scientific therapies to help maintain optimal health and slow aging. The medical literature contains thousands of references on the use of antioxidant vitamins, weight loss supplements, and hormones that have been shown to improve the quality and quantity of life. Life Extensionists attempt to take advantage of this scientific information to enhance their changes of living longer in good health. This article is posted by permission of Life Extension. https://www.lifeextension.com/

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                      This website is for informational and entertainment purposes only and is not a substitute for medical advice, diagnosis or treatment. FoodTrients – A Recipe for Aging Beautifully Grace O, author and creator of FoodTrients® -- a philosophy, a cookbook and a resource -- has a new cookbook dedicated to age-defying and delicious recipes, The Age Beautifully Cookbook: Easy and Exotic Longevity Secrets from Around the World, which provides one hundred-plus recipes that promote health and well-being. The recipes are built on foundations of modern scientific research and ancient knowledge of medicinal herbs and natural ingredients from around the world. Since the publication of her first anti-aging book, The Age GRACEfully Cookbook, Grace O has identified eight categories of FoodTrients benefits (Anti-inflammatory, Antioxidant, Immune Booster, Disease Prevention, Beauty, Strength, Mind, and Weight Loss) that are essential to fighting aging, which show how specific foods, herbs, and spices in the recipes help keep skin looking younger, prevent the diseases of aging, and increase energy and vitality. Grace O combines more exotic ingredients that add age-fighting benefits to familiar recipe favorites.

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