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                      Vitamin D essential to combat TB

                      Published by Life Extension

                      In an article published online on October 12, 2011 in Science Translational Medicine Dr Robert Modlin and his colleagues at the University of California, Los Angeles report an essential role for vitamin D in the body’s ability to fight tuberculosis (TB).

                      The rate of infection for tuberculosis is highest in certain areas of Africa–a fact that may be due to a reduced ability to manufacture vitamin D among individuals with darker skin. In previous research conducted by the team, the vitamin was found to be involved in the production of cathelicidin, which aids the innate immune system’s response to tuberculosis infection. In the current study, Dr Modlin and his colleagues discovered that it is necessary to have a sufficient amount of vitamin D in the body in order for white blood cells known as T-cells to release interferon-gamma, which directs infected immune cells to attack the tuberculosis bacteria. When the team subsequently tested the immune responses of blood samples obtained from humans with and without sufficient vitamin D levels, serum from those with vitamin D insufficiency failed to stimulate an immune response; however, the response was restored upon the addition of vitamin D.

                      “The role of interferon has been speculated for years in numerous studies, but previous research didn’t take into account that sufficient vitamin D was needed to help interferon-gamma trigger an effective immune response,” stated study coauthor Dr John Adams. “Now we understand better how this chain reaction works.”

                      “Over the centuries, vitamin D has intrinsically been used to treat tuberculosis,” noted first author Mario Fabri. “Sanatoriums dedicated to tuberculosis patients were traditionally placed in sunny locations that seemed to help patients — but no one knew why this worked.”

                      “Our findings suggest that increasing vitamin D levels through supplementation may improve the immune response to infections such as tuberculosis,” he concluded.

                       

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                      Life Extension
                      Life Extension
                      LIFE EXTENSION The Life Extension Health News team delivers accurate information about vitamins, nutrition and aging. Our stories rely on multiple, authoritative sources and experts. We keep our content accurate and trustworthy, by submitting it to a medical reviewer. Life Extensionists are people who believe in taking advantage of documented scientific therapies to help maintain optimal health and slow aging. The medical literature contains thousands of references on the use of antioxidant vitamins, weight loss supplements, and hormones that have been shown to improve the quality and quantity of life. Life Extensionists attempt to take advantage of this scientific information to enhance their changes of living longer in good health. This article is posted by permission of Life Extension. https://www.lifeextension.com/

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                      This website is for informational and entertainment purposes only and is not a substitute for medical advice, diagnosis or treatment. FoodTrients – A Recipe for Aging Beautifully Grace O, author and creator of FoodTrients® -- a philosophy, a cookbook and a resource -- has a new cookbook dedicated to age-defying and delicious recipes, The Age Beautifully Cookbook: Easy and Exotic Longevity Secrets from Around the World, which provides one hundred-plus recipes that promote health and well-being. The recipes are built on foundations of modern scientific research and ancient knowledge of medicinal herbs and natural ingredients from around the world. Since the publication of her first anti-aging book, The Age GRACEfully Cookbook, Grace O has identified eight categories of FoodTrients benefits (Anti-inflammatory, Antioxidant, Immune Booster, Disease Prevention, Beauty, Strength, Mind, and Weight Loss) that are essential to fighting aging, which show how specific foods, herbs, and spices in the recipes help keep skin looking younger, prevent the diseases of aging, and increase energy and vitality. Grace O combines more exotic ingredients that add age-fighting benefits to familiar recipe favorites.

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