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August 7, 2018
On July 2, 2018, The Journal of Neuroscience reported the discovery of an ability of aspirin to decrease amyloid beta plaque in a mouse model of Alzheimer’s disease. The presence in the brain of amyloid beta plaques, along with neurofibrillary tangles made up of hyperphosphorylated tau protein, are among the characteristics of Alzheimer’s disease in humans. Dr Pahan and colleagues determined that aspirin upregulates transcription factor EB (TFEB), a regulator of lysosome formation. “Lysosomes play a central role in cellular homeostasis by regulating the cellular degradative machinery,” lead researcher Kalipada Pahan, PhD, and colleagues explain. “Since aberrant lysosomal function has been associated with […]
March 15, 2017
Aspirin’s association with a lower risk of numerous types of cancer has been attributed to its anti-inflammatory effect; however, research reported in the February 2017 issue of Cancer Prevention Research suggests another potential mechanism. In experiments utilizing colon cancer cells and a mouse model of colon cancer, Houston researchers observed that aspirin prevented the cancer-promoting interaction between cancer cells and platelets by inhibiting cyclooxygenase-1 (COX-1)-mediated platelet activation. Platelets are involved in the formation of new blood vessels which, although beneficial in most cases, enhances tumor growth. While common aspirin was used in some of the experiments, other experiments utilized a complex […]
August 11, 2015
If you’re a woman over 50 and you have a family history of melanoma, you’ll want to know the new findings about an old, simple pain reliever. Researchers have found that it may cut your risk of developing melanoma 30% and more the longer you take it. Here’s what you should know… Melanoma Risk? Study Shows Aspirin Can Help Aspirin is a simple pain relieving compound that has been used for decades for headaches, fever, muscle cramps, and more. Even though aspirin is a manufactured “drug”, its active ingredient, salicin, is actually derived from white willow bark, a natural herb. […]
June 16, 2015
For my patients who are at high risk for a heart attack or stroke, I’ve sometimes recommended a simple daily aspirin for prevention. But, recently, it was learned that over half of U.S. seniors are taking daily aspirin on their own without their doctors recommendation. If you’re one of those seniors, here’s what you should know about using aspirin for prevention. Daily Aspirin as Prevention: Pros and Cons A recent national survey was conducted by Oregon State University regarding aspirin use amongst seniors. They found that an overwhelming majority of seniors – 81% – take aspirin as a preventative measure. […]
May 12, 2015
Many of my patients are age 60 and over and as such they have specific health issues. One of their concerns is the healthcare of their eyes and preserving their vision. Recently, I became aware of a study published in Ophthalmology Magazine that warned of people over 60 developing a vision-affecting disease called wet-type macular degeneration. The study found that people who regularly take aspirin for certain health issues had a doubled risk of developing blindness from wet-type ARMD (age-related macular degeneration). I’d like to share this warning with you as I have my own patients to hopefully prevent anyone from damaging their vision […]