Chronic liver disease appears to be promoted by taking stomach acid blockers known as proton pump inhibitors, according to a study led by University of California San Diego researchers. The drugs, including such best-sellers as Prilosec, Nexium and Prevacid, change the population of gut microbes. This leads to overgrowth of a bacterium that causes liver inflammation and cell death, the study found. The study was published in Nature Communications. It was performed with mouse models, healthy human volunteers, and data from chronic alcoholics. Bernd Schnabl, M.D., was the study’s senior author. Cristina Llorente, also of UCSD, was first author. Proton pump inhibitors are the most effective […]