March 21, 2017
Published by Life Extension

Tyrosine and Tryptophan Fight “Baby Blues”

A study reported on March 13, 2017 in the Proceedings of the National Academy of Sciences found a lower risk of early postpartum blues among women who received the amino acids tyrosine and tryptophan, and an extract of blueberries. The condition peaks on the fifth day after giving birth and is a risk factor for long term postpartum depression. Levels of a compound known as monoamine oxidase A become elevated in the brain during postpartum blues, resulting in increased breakdown of norepinephrine, serotonin and dopamine, which can be deficient in depressed states. While tyrosine is a precursor to norepinephrine and dopamine, […]
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March 21, 2017
Published by Life Extension

‘Late-Life’ Genes Activated by Biological Clock

Researchers at Oregon State University have discovered that a subset of genes involved in daily circadian rhythms, or the “biological clock,” only become active late in life or during periods of intense stress when they are most needed to help protect critical life functions. The findings, made in research done with fruit flies and published today in Nature Communications, are part of a unique stress response mechanism that was previously unknown. These genes may help to combat serious stresses associated with age, disease or environmental challenges, and help explain why aging is often accelerated when the biological clock is disrupted. […]
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March 15, 2017
Published by Life Extension

Grapes Could Help Protect Cognitive Decline

The January 2017 issue of Experimental Gerontology published the finding of researchers at the University of California, Los Angeles of a protective effect for powdered grape against a decline in brain metabolism in older adults. The results of the investigation suggest that eating grapes might contribute to the prevention of Alzheimer’s disease. The study included ten men and women with mild cognitive decline. Participants were given freeze-dried grape powder or a placebo similar in flavor and appearance but lacking beneficial grape polyphenols. The grape powders, which provided the equivalent of three servings of grapes per day, were mixed with water […]
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March 15, 2017
Published by Life Extension

How Aspirin Works Against Cancer

Aspirin’s association with a lower risk of numerous types of cancer has been attributed to its anti-inflammatory effect; however, research reported in the February 2017 issue of Cancer Prevention Research suggests another potential mechanism. In experiments utilizing colon cancer cells and a mouse model of colon cancer, Houston researchers observed that aspirin prevented the cancer-promoting interaction between cancer cells and platelets by inhibiting cyclooxygenase-1 (COX-1)-mediated platelet activation. Platelets are involved in the formation of new blood vessels which, although beneficial in most cases, enhances tumor growth. While common aspirin was used in some of the experiments, other experiments utilized a complex […]
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February 28, 2017
Published by Life Extension

The Power Of Tea

A compound found in green tea could have lifesaving potential for patients with multiple myeloma and amyloidosis, who face often-fatal medical complications associated with bone-marrow disorders, according to a team of engineers at Washington University in St. Louis and their German collaborators. Jan Bieschke, assistant professor of biomedical engineering at the School of Engineering & Applied Science, studies how proteins fold and shape themselves, and how these processes can contribute to a variety of diseases. He says the compound epigallocatechine-3-gallate (EGCG), a polyphenol found in green tea leaves, may be of particular benefit to patients struggling with multiple myeloma and […]
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February 28, 2017
Published by Life Extension

Vitamin D Supplements Help Relieve Chronic Back Pain

A clinical trial reported in the January 2017 issue of Pain Physician uncovered a benefit for supplementing with vitamin D among individuals with chronic lower back pain. The condition is the second most common pain complaint after headache and can be notoriously resistant to treatment. The trial included 68 men and women who had chronic lower back pain for at least three months that did not respond to medications and physical therapy. Subjects were limited to those with plasma 25-hydroxyvitamin D3 levels measured at the beginning of the trial of less than 30 nanograms per milliliter (ng/mL). Participants received 60,000 […]
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February 21, 2017
Published by Life Extension

High-altitude Living Cuts Diabetes Risk

A major risk factor for development of heart diseases, strokes and diabetes is lower in people who live at higher altitudes, says a new study that suggests that something as simple as the geographic area in which you live contribute to your risk of developing these diseases. “We found that those people living between 1500 to 7536 feet, had a lower risk of developing Metabolic Syndrome than those living at sea level (zero to 396 feet),” said Amaya Lopez-Pascual, who conducted this research as part of her PhD thesis at University of Navarra, Spain. Metabolic syndrome is the medical term for the […]
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