The June 14, 2017 issue of Science Translational Medicine published the finding of an ability for sulforaphane, a compound that occurs in broccoli and other vegetables, to lower the liver’s production of glucose. By comparing gene signatures for diabetes with the potential ability of 3,852 compounds to affect these genes, Anders Rosengren and colleagues identified sulforaphane as having the highest overlap. “A large number of genetic variants and tissue gene expression profiles (“disease signatures”) have been associated with complex polygenic diseases over the last decade,” the authors explain. “One potentially interesting approach is to use genetic and gene expression data […]