A report published on January 9, 2019 in Nature Communications suggests a benefit for urolithin A, a metabolite derived from pomegranate and berries, in the prevention and treatment of inflammatory bowel diseases (IBD), which include Crohn’s disease and ulcerative colitis and are characterized by inflammation due to gut leakage of toxins. “Urolithin A (UroA), a major microbial metabolite derived from polyphenolics of berries and pomegranate fruits displays anti-inflammatory, antioxidative, and anti-aging activities,” write Rabir Singh of the University of Louisville and colleagues. “Here, we show that urolithin A and its potent synthetic analogue (UAS03) significantly enhance gut barrier function and inhibit unwarranted inflammation.” “Microbiota […]