August 7, 2018
Published by Life Extension

Low Dose Aspirin Could Help Treat Alzheimer’s Disease

On July 2, 2018, The Journal of Neuroscience reported the discovery of an ability of aspirin to decrease amyloid beta plaque in a mouse model of Alzheimer’s disease. The presence in the brain of amyloid beta plaques, along with neurofibrillary tangles made up of hyperphosphorylated tau protein, are among the characteristics of Alzheimer’s disease in humans. Dr Pahan and colleagues determined that aspirin upregulates transcription factor EB (TFEB), a regulator of lysosome formation. “Lysosomes play a central role in cellular homeostasis by regulating the cellular degradative machinery,” lead researcher Kalipada Pahan, PhD, and colleagues explain. “Since aberrant lysosomal function has been associated with […]
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July 24, 2018
Published by Life Extension

Is Poor Diet Behind The Teenage Mental Health Crisis?

Fiona Hunter, one of the UK’s leading nutritionists, takes a look at the possible correlation between the emerging mental health crisis in teenagers and how this could be linked to the lack of vital vitamins and minerals in teenagers. This week, research found that young people aged 16 to 25 are the unhappiest generation in a decade, with one in four feeling ‘hopeless’ on a regular basis, and nearly half having experienced a mental health problem. Eating a healthy balanced diet is not usually high up on the ‘to-do’ list for most teenagers and young adults – one reason is […]
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July 24, 2018
Published by Life Extension

Baking Soda Improves Cancer Treatment?

Consuming baking soda may help immunotherapy drugs to fight difficult-to-treat tumors. This cheap and simple intervention may eventually improve current cancer treatments. Baking soda could help to boost immunotherapy. Within tumors, large portions are deprived of oxygen. Scientists know that these hypoxic regions tend to be the most resistant to treatment. If a cell is unable to access adequate oxygen, it slows down and enters what is known as a quiescent state. The molecular switch mTORC1 is responsible for assessing the situation before telling the cell whether or not it should divide. If mTORC1 is not present, the cell’s internal […]
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July 10, 2018
Published by Life Extension

Green Tea’s Secret Property Could Benefit Arteries

A report appearing on June 1, 2018 in the Journal of Biological Chemistry suggests that the green tea compound epigallocatechin-3-gallate (EGCG) could help dissolve atherosclerotic plaque associated with heart attack and stroke. The compound is currently under investigation in regard to its ability to reduce amyloid plaque in the brain, which is associated with Alzheimer’s disease. Researchers at Lancaster University and the University of Leeds found that EGCG binds to the amyloid fibers of apolipoprotein A-1 (apoA-1), which can form amyloid deposits in arterial plaques similar to those that occur in the brains of Alzheimer’s disease patients. These deposits enlarge plaque and make […]
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July 7, 2018
Published by Life Extension

New Ways To Reduce Inflammation

When most people think of inflammation, they think about swollen joints and arthritis. That said, limiting the amount of inflammation in your body might not be on your radar screen at all, especially if you don’t have joint problems. But inflammation is way more than arthritis, and reducing the amount of inflammation your body encounters should be on everyone’s radar. When any unwanted invader (such as a virus or bacteria) enters your body, inflammation is the body’s first line of defense. White blood cells are soldiers in the inflammation army, and they protect your body when it’s attacked. This is […]
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