January 8, 2019
In an article published on November 21, 2018 in the Journal of Applied Physiology, University of Nebraska Medical Center researchers reported the outcome of a study which suggests that curcumin, a compound occurring in the spice turmeric, could help heart failure patients with exercise intolerance. “We hypothesized that reduced expression of nuclear factor E2-related factor 2 (Nrf2) in skeletal muscle contributes to impaired exercise performance,” explain Ahmed M. Wafi and colleagues. “We further hypothesized that curcumin, a Nrf2 activator, would preserve or increase exercise capacity in heart failure.” “Although curcumin has been evaluated in several clinical trials for multiple diseases, its therapeutic potential […]