April 16, 2019
Published by Life Extension

Counting Calories Could Prevent Diseases

Research presented on February 11, 2019 at FAPESP (São Paulo Research Foundation) Week London supports the potential for calorie restriction to protect against several diseases. The studies were conducted under the auspices of the Center for Research on Redox Processes in Biomedicine, which is funded by FAPESP. “We are looking at how changes to the diet affect metabolism and how that ends up changing the odds of having diseases associated with aging,” commented researcher Alicia Kowaltowski, of the University of São Paulo. In one experiment, a group of mice was allowed to consume as much food as they desired, and the number […]
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April 2, 2019
Published by Life Extension

Vitamin C Supplements Shorten ICU Stays

The April 2019 issue of Nutrients published the findings of a meta-analysis which concluded that the administration of vitamin C to intensive care unit (ICU) patients shortened the patients’ stay by an average of 7.8%. Dr Harri Hemilä of the University of Helsinki, Finland, and Dr Elizabeth Chalker of the University of Sydney, Australia, selected 12 controlled trials that included a total of 2,004 patients for their analysis. While subjects who received orally administered vitamin C had an ICU stay that was 7.8% shorter than that of patients who did not receive the vitamin, patients in six trials who received an average […]
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April 2, 2019
Published by Life Extension

Scientists Identify ‘Origin’ of Cancer Spread

Scientists at the University of Salford said they have identified a cancer cell from which all cancer growth starts in the body. The ‘cell of origin’ thought to trigger all types of cancer and allow the disease to spread has been found, scientists claim. Salford University researchers have described their discovery as being like managing to find the proverbial ‘needle in a haystack’. But the findings, hoped to rewrite medical textbooks on the growth of cancer, could be a blow to existing treatments, such as chemotherapy. Professor Michael Lisanti, study author, said: ‘We may have to press the reset button on how we treat […]
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March 19, 2019
Published by Life Extension

Zinc Deficiency Linked to Hypertension

An article appearing on January 16, 2019 in the American Journal of Physiology–Renal Physiology  reported that deficient zinc levels may contribute to high blood pressure by promoting sodium re-absorption by the kidneys. Zinc deficiency is common in many chronic diseases and can worsen hypertension. However, it had not been known whether zinc deficiency alone could impact blood pressure. In the current study, the researchers fed 20 mice diets that contained adequate amounts of zinc for two weeks, after which 15 animals were given zinc deficient diets for five to six weeks. Five of these deficient animals were subsequently returned to diets that provided […]
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March 5, 2019
Published by Life Extension

Intermittent Fasting Boosts Health

Various versions of the intermittent fasting diet appear to have weight loss benefits. A new study investigating why they work concludes that circadian rhythms are key. Intermittent fasting has become popular, but how does it work? While the modern world appears awash with fad diets, people seem to be giving a fair bit of attention to intermittent fasting. As its name implies, intermittent fasting involves eating nothing for extended periods of time. Some studies have found that this type of diet is beneficial, but exactly why it benefits health is not yet clear. Recently, a group of scientists at the University […]
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February 19, 2019
Published by Life Extension

Pomegranate Metabolite Is Good For Your Gut

A report published on January 9, 2019 in Nature Communications suggests a benefit for urolithin A, a metabolite derived from pomegranate and berries, in the prevention and treatment of inflammatory bowel diseases (IBD), which include Crohn’s disease and ulcerative colitis and are characterized by inflammation due to gut leakage of toxins. “Urolithin A (UroA), a major microbial metabolite derived from polyphenolics of berries and pomegranate fruits displays anti-inflammatory, antioxidative, and anti-aging activities,” write Rabir Singh of the University of Louisville and colleagues. “Here, we show that urolithin A and its potent synthetic analogue (UAS03) significantly enhance gut barrier function and inhibit unwarranted inflammation.” “Microbiota […]
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February 19, 2019
Published by Life Extension

Vitamin C Shows Promise As Brain Aging Treatment

A study reported on January 9, 2019 in the journal Nutrients revealed a protective role for supplementation with vitamin C, a well known antioxidant, in mice exposed to D-galactose, a sugar that occurs in some foods which has been shown to induce brain aging via the accumulation of oxidative stress. One hundred-eight mice were divided to receive subcutaneous D-galactose or no D-galactose for 10 weeks. Beginning in the seventh week, half of the animals in each group were given a high oral dose of vitamin C for four weeks. While mice that received D-galactose experienced a reduction in cognitive function and decreased neurogenesis in […]
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February 5, 2019
Published by Life Extension

Exercise Hormone May Protect Against Alzheimer’s

A hormone released during exercise may protect the brain against Alzheimer’s disease, research suggests. Irisin is a messenger protein generated by muscle tissue that is carried around the body in the bloodstream. The new evidence indicates that it may be behind the known positive effects on mental performance of taking exercise. US and Brazilian scientists found lower levels of the hormone in the brains of Alzheimer’s patients compared with healthy individuals. The same was true for the precursor protein from which irisin is derived, FNDC5. In tests on genetically engineered mice, the scientists induced learning and memory deficits by cutting […]
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